Efficient genome editing of human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

Published on August 2014 in Nature Biotechnology

Ghorbal, M, Gorman, M, Macpherson, CR, Miyazawa Martins, R, Scherf, A, and Lopez-Rubio, JJ

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Published on April 2015 in Nature

Mbengue A, Bhattacharjee S, Pandharkar T, Liu H, Estiu G, Stahelin RV, Rizk SS, Njimoh DL, Ryan Y, Chotivanich K, Nguon C, Ghorbal M, Lopez-Rubio JJ, Pfrender M, Emrich S, Mohandas N, Dondorp AM, Wiest O, Haldar K

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Discovery of a novel and conserved Plasmodium falciparum exported protein that is important for adhesion of PfEMP1 at the surface of infected erythrocytes

Published on August 2015 in Cell Microbiol

Nacer A, Claes A, Roberts A, Scheidig-Benatar C, Sakamoto H, Ghorbal M, Lopez-Rubio JJ, Mattei D

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First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites

Published on October 2015 in Cell Microbiol

Sollelis L, Ghorbal M, MacPherson CR, Martins RM, Kuk N, Crobu L, Bastien P, Scherf A, Lopez-Rubio JJ, Sterkers Y

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Telomere´s structure and function

Published on March 2016 in Book Chapter in Encyclopedia of Malaria, Springer. Editors Hommel M and Kremsner PG

Mancio-Silva L and Lopez-Rubio JJ

The strong interest of the parasitology community on our adaptation of the CRISPR/Cas system in P. falciparum led us to organize an international workshop in June 2014 in order to share this technological breakthrough. CRISPRcourse We would like to thank our funders who are currently supporting, or have in the past supported, our research: